Liver disease and liver failure is considered the 4th commonest cause of death in the world and the death count from liver cirrhosis seem to be rapidly rising. Currently the only effective and natural option for end-stage liver disease is liver stem cell treatment. The alternative is liver transplants but that carries its own risks. Alternative therapeutic strategies like hepatocyte cell transplants seem to be the most effective treatment for advanced liver failure.
Under normal conditions a human liver regenerates itself through cell division of mature hepatocyte cells. In chronic liver failure, this capacity has failed and require the assistance of Hepatic Progenitor Cells (HPCs or oval cells). These progenitor stem cells can help create both hepatocytes cells and biliary epithelium cells needed in recovering from liver failure.
